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Immunologist Specialist Series – Glabe Lab

Application Window

Open date: January 11th, 2021

Last review date: Monday, Feb 15, 2021 at 11:59pm (Pacific Time)
Applications received after this date will be reviewed by the search committee if the position has not yet been filled.

Final date: Wednesday, Jun 30, 2021 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.

Position description

The Department of Molecular Biology and Biochemistry in the School of Biological Sciences is accepting applications in the areas of adaptive or innate immunology and neuroinflammation in relationship to Alzheimer’s disease. The person in the position will perform experiments with human brain samples cultured neurons and transgenic mice under the direction of Dr. Charles Glabe. This NIH-funded project examines natural antibodies (NA) and autoantibodies (AA) that are correlated with the incidence or avoidance of Alzheimer’s disease and the pathological significance of the immune response to amyloid. The overarching hypothesis is that the immune response to amyloid is similar to the immune response to microbial pathogens, where NA are produced by a T cell independent immune response and forms first response to the formation of amyloids. We hypothesize that NA and AA are associated with protection against AD and may serve as biomarkers of AD. This person also will work on the role of inflammatory cell death pathways in the pathogenesis of AD. Renewal of the appointment will be contingent on performance and the availability of adequate funding.

The University of California, Irvine is ranked among the nation’s best research institutes with over $90,000,000 in current funding. Enrichment opportunities abound through the Alzheimer’s Disease Research Center, the Memory Impairment and Neurodegenerative Disease Institute and the Center for the Neurobiology of Learning and Memory. Irvine has a pleasant climate, five miles from the beach.

Ph.D. in immunology, neuroscience or cell biology and an interest in Alzheimer’s disease is preferred. Experience with monoclonal antibodies, inflammation and experience working with transgenic mice is ideal. Experience with informatics is also desired.
Candidate performs research in a specialized area, provides university and public service, demonstrates professional competency and activity.

Qualified candidates should submit their curriculum vitae, a cover letter, and the names and contact information of three references to the following on-line recruitment URL:

The University of California, Irvine is an Equal Opportunity/Affirmative Action Employer advancing inclusive excellence. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC nondiscrimination policy.

Application Requirements

Document requirements
Reference requirements
  • 3-5 required (contact information only)

Job location

Irvine, CA