POSTDOCTORAL SCHOLAR - NEUROLOGICAL ONCOLOGIST

A Postdoctoral position is available immediately in the Neurological Oncology Laboratory (Bota, PI) at the Department of Neurology, University of California, Irvine. The candidate should have a recent Ph.D. in biomedical sciences and expertise in cancer biology, molecular biology, and animal tumor models. The applicant would participate in studies investigating novel strategies to limit glioblastoma tumor growth and to overcome resistance to current therapies.

The Bota Lab is renowned for expertise in translational neuro-oncology research. The overarching mission of the Bota Laboratory is to further develop novel chemotherapeutic and immune-based therapies for the treatment of glioblastoma. The laboratory has a proven track-record of obtaining competitive R01 funding. They use patient-derived GBM cells and glioma stem-like cells (GSCs), PDX models, organoids, to study mechanisms of GBM treatment resistance and invasion.

Potential projects in the Bota Lab include:
• Development of CAR-T cell-based therapies for GBM
• Patient-derived GBM organoid models
• Development of mitochondrial-targeted therapies for GBM

Requirements:
• Recent or anticipated PhD or equivalent degree
• Experience in cancer biology, neuroscience, and/or immunology is desirable
• Excellent written and oral communication skills
• Collaborative: performs as a team member with good interpersonal skills
• Strong analytical and organizational skills; detail-oriented
• Publication in peer-reviewed journals
• Ability to work independently and in a multidisciplinary team
• Contribute to grant writing

Preferred Qualifications:
Applicants who have knowledge of brain tumors, mitochondrial biology, immunology, CAR-T cell development, and pre-clinical drug testing are especially encouraged to apply. Successful applicants will be self-motivated, team players, and have a passion for science.

Substantive inquiries about the positions should be directed to:
Daniela Bota, MD, PhD
Medical Director
UCI Center for Clinical Research
200 S. Manchester Ave., Suite 206
[dbota@hs.uci.edu]

TO APPLY: Please log onto UCI’s RECRUIT located at [https://recruit.ap.uci.edu/JPF07772]

Applicants should complete an online application profile and upload the following application materials electronically to be considered for the position:

1. Cover letter—Please discuss current research and future plans.
2. Curriculum Vitae
3. Names and Contact Information of Three References
4. Research Statement

The University of California, Irvine is an Equal Opportunity/Affirmative Action Employer advancing inclusive excellence. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC nondiscrimination policy.

As a condition of employment, you will be required to comply with the University of California Policy on Vaccination Programs – With Updated Interim Amendments. All Covered Individuals under the policy must provide proof of receiving the COVID-19 Vaccine Primary Series or, if applicable, submit a request for Exception (based on Medical Exemption, Disability, Religious Objection, and/or Deferral based on pregnancy or recent COVID-19 diagnosis and/or treatment) no later than the applicable deadline. All Covered Individuals must also provide proof of receiving the most recent CDC-recommended COVID-19 booster or properly decline such booster no later than the applicable deadline. New University of California employees should refer to Exhibit 2, Section II.C. of the SARS-CoV-2 (COVID-19) Vaccination Program Attachment for applicable deadlines. All Covered Individuals must also provide proof of being up-to-date on seasonal influenza vaccination or properly decline such vaccination no later than the applicable deadline. Please refer to the Seasonal Influenza Vaccination Program Attachment. (Capitalized terms in this paragraph are defined in the policy.) Federal, state, or local public health directives may impose additional requirements.