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Project Scientist in Chemistry - UCI Institute for Neurotherapeutics

Application Window

Open date: September 6, 2022

Most recent review date: Thursday, Oct 6, 2022 at 11:59pm (Pacific Time)
Applications received after this date will be reviewed by the search committee if the position has not yet been filled.

Final date: Saturday, Dec 31, 2022 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.

Position description

We are seeking a PhD-level chemist with excellent organic synthesis expertise to support high throughput screening and library design within the UCI Institute for Neurotherapeutics (UCI-INT).

In this laboratory-based position, the successful candidate will work within the UCI-INT chemistry group. Efforts of the successful applicant are expected to expand as with members of our broader screening and informatics teams enable full end-to-end chemical/high-throughput screening. The ideal candidate will oversee early discovery and hit expansion library design, plan and execute library and hit synthesis, and manage smaller compound collections (compound registration, interpret/organize structural characterization and bioassay data).
The main goals of the UCI-INT are to: 1) foster meaningful interactions between neuroscience / neurological disease researchers and UCI faculty who aim to expedite translational research, and 2) to bring together neuroscience / neurological disease researchers with UCI clinical colleagues, whose academic and patient care interests align with ongoing research efforts at the bench to accelerate translation to the bedside.

Responsibilities of the Project Scientist include:
• Maintaining a high level of productivity in the laboratory setting.
• Working with autonomy to design experiments, interpret data, and propose next steps.
• Developing and conducting aqueous chemical reactions on DNA–small molecule conjugates.
• Analyzing DNA-chemical conjugate compositions through mass spectrometry and other analytical techniques.
• Sourcing of materials required for chemical library synthesis.
• Hit synthesis and characterization for follow-on formal biological activity assays.
• Coordinating library and hit resynthesis with external synthetic resources.
• Working on novel, testable hypotheses to enable clear decision making.
• Contributing to scientific strategies and goals within a team setting.
• Presenting data and reports on project status at individual and group meetings.
• Generating data for and serving as co-author on research published in peer reviewed journals and presenting work at scientific conferences
• Training junior chemists to perform subsets of the above tasks
Qualifications
• A Ph.D. is required, in chemistry or related subject area or currently in a corresponding PhD program with an anticipated graduation / completed degree by Summer, 2022.
• A strong track record of achievement in synthetic chemistry through peer reviewed publications, patents and presentations and a deep knowledge of modern synthetic and analytical techniques is required.
• Intellectual curiosity to improve established methods and explore new laboratory workflows is required.
• Excellent oral and written communication skills, including preparation of presentations is required.

To apply via AP Recruit, please go here: https://recruit.ap.uci.edu/JPF07877 to upload Cover letter, CV and Inclusive Excellence/Contributions to Diversity Statement.

Qualifications

Basic qualifications (required at time of application)

• A Ph.D. is required, in chemistry or related subject area or currently in a corresponding PhD program with an anticipated graduation / completed degree by Summer, 2022.
• A strong track record of achievement in synthetic chemistry through peer reviewed publications, patents and presentations and a deep knowledge of modern synthetic and analytical techniques is required.
• Intellectual curiosity to improve established methods and explore new laboratory workflows is required.
• Excellent oral and written communication skills, including preparation of presentations is required.

Application Requirements

Document requirements
Apply link: https://recruit.ap.uci.edu/JPF07877

Campus Information

The University of California, Irvine is an Equal Opportunity/Affirmative Action Employer advancing inclusive excellence. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC nondiscrimination policy.

Job location

Irvine, Ca.