Recruit

The University of California, Irvine's Institute for Memory Impairments and Neurological Disorders (UCI MIND) has an opportunity for a Postdoctoral Scholar. The mission of UCI MIND is to engage in cutting edge, interdisciplinary research designed to discover the basic mechanisms of neurodegeneration and brain aging, characterize the transition from normal aging to Alzheimer’s disease, and develop new treatments to slow or eliminate cognitive impairment resulting from any etiology. This position is within the UCI Model Organism Development and Evaluation for Late-onset Alzheimer’s disease (MODEL-AD) project. MODEL-AD is a NIA/NIH-funded multi-project, multi-institutional grant whose goal is to produce the next generation of mouse models for late-onset AD and develop new therapeutic targets. Projects will be centered around the generation and phenotyping of new mouse models of late onset AD, based on identified risk variants from human studies. Endpoints include behavioral and cognitive testing, histopathology, biochemistry, RNA-seq, spatial gene expression and protein analyses, and alignment with human data. These models will be utilized to understand the biology that leads to the development of AD in the aged brain.

Requirements

The successful candidate will have a PhD with a minimum of 2 years of experience in the field of neuroscience. The candidate must have experience with animal models of Alzheimer's disease with extensive knowledge of animal surgery, behavioral, biochemical and imaging assays. Experience with beta-amyloid and tau interaction and synaptic loss within Alzheimer’s disease models is highly desirable, as well as the role of inflammation and glia in the context of AD models. The applicant must have the ability to work independently, meet deadlines, and oral and written communication skills are essential. This position will be appointed at the level that is commensurate with the education and experience of the individual candidate.

Application Procedure

Please submit a letter of interest, curriculum vitae which should include a record of research experience and the names of three references before 3/24/23 to:

https://recruit.ap.uci.edu/apply/JPF08127

The University of California, Irvine is an Equal Opportunity/Affirmative Action Employer advancing inclusive excellence. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC nondiscrimination policy.

As a condition of employment, you will be required to comply with the University of California Policy on Vaccination Programs – With Updated Interim Amendments. All Covered Individuals under the policy must provide proof of receiving the COVID-19 Vaccine Primary Series or, if applicable, submit a request for Exception (based on Medical Exemption, Disability, Religious Objection, and/or Deferral based on pregnancy or recent COVID-19 diagnosis and/or treatment) no later than the applicable deadline. All Covered Individuals must also provide proof of receiving the most recent CDC-recommended COVID-19 booster or properly decline such booster no later than the applicable deadline. New University of California employees should refer to Exhibit 2, Section II.C. of the SARS-CoV-2 (COVID-19) Vaccination Program Attachment for applicable deadlines. All Covered Individuals must also provide proof of being up-to-date on seasonal influenza vaccination or properly decline such vaccination no later than the applicable deadline. Please refer to the Seasonal Influenza Vaccination Program Attachment. (Capitalized terms in this paragraph are defined in the policy.) Federal, state, or local public health directives may impose additional requirements.