Recruit

The Byun Laboratory at UCI has an open position for a Specialist who will contribute to the ongoing projects investigating the molecular link between epigenetic modifier mutations in immune cells and diseases associated with them.

The current research focus of the Byun laboratory is on the impact of mutations in epigenetic modifiers on the pathogenesis of associated growth syndromes (inherited mutations) and aging-related immune dysfunction (acquired mutations). The final candidate will have a chance to contribute to both aspects of this research.

This position will carry out 1) maintenance of human pluripotent stem cells (hPSCs), 2) genome editing of hPSCs, and 3) in vitro differentiation of hPSCs to immune cells, using the standard as well as specialized mammalian tissue culture techniques and molecular biology techniques. Necessary training for the specialized techniques related to hPSC cultures and their genome editing will be provided. Additionally, this position will include shared responsibilities such as general laboratory management, ordering, receiving, distributing laboratory supplies, equipment maintenance, and other tasks related to laboratory upkeep.

Candidates with the following experience are strongly encouraged to apply:
-Standard mammalian cell culture and standard molecular biology techniques.
-Background exposure to fields of immunology, genetics, stem cell biology, and epigenetics.
-Broad exposure to diverse techniques in cell culture (e.g. pluripotent stem cell differentiation, primary cell culture).
-Broad exposure to diverse techniques in genetics and genomics (e.g. multiplex PCR, next-gen sequencing library preparation).
-Familiarity with optimizing/troubleshooting experimental protocols.

The University of California, Irvine is an Equal Opportunity/Affirmative Action Employer advancing inclusive excellence. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC nondiscrimination policy.

As a condition of employment, you will be required to comply with the University of California Policy on Vaccination Programs – With Updated Interim Amendments. All Covered Individuals under the policy must provide proof of receiving the COVID-19 Vaccine Primary Series or, if applicable, submit a request for Exception (based on Medical Exemption, Disability, Religious Objection, and/or Deferral based on pregnancy or recent COVID-19 diagnosis and/or treatment) no later than the applicable deadline. All Covered Individuals must also provide proof of receiving the most recent CDC-recommended COVID-19 booster or properly decline such booster no later than the applicable deadline. New University of California employees should refer to Exhibit 2, Section II.C. of the SARS-CoV-2 (COVID-19) Vaccination Program Attachment for applicable deadlines. All Covered Individuals must also provide proof of being up-to-date on seasonal influenza vaccination or properly decline such vaccination no later than the applicable deadline. Please refer to the Seasonal Influenza Vaccination Program Attachment. (Capitalized terms in this paragraph are defined in the policy.) Federal, state, or local public health directives may impose additional requirements.