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Amyloid Protein Biochemist Researcher – Glabe Lab

Position overview

Salary range: A reasonable estimate for this position is $83,300-$221,800. See Professional Researcher Series– Represented Fiscal Year

Application Window

Open date: May 5, 2023

Most recent review date: Thursday, Feb 29, 2024 at 11:59pm (Pacific Time)
Applications received after this date will be reviewed by the search committee if the position has not yet been filled.

Final date: Tuesday, Apr 30, 2024 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.

Position description

The Department of Molecular Biology and Biochemistry in the School of Biological Sciences is accepting applications in the area protein biochemistry / structural biology related to Alzheimer’s disease. The person in the position will perform experiments with human brain samples and transgenic mice and amyloid fibrils and oligomers formed from synthetic and recombinant purified proteins under the direction of Dr. Charles Glabe. This NIH-funded project aims at developing methods for the purification and preparation of homogeneous amyloid oligomers and fibrils of different structural polymorphs and tools for studying amyloid polymorphism in vitro and in vivo. The hypothesis to be examined is that different types of amyloid accumulate in different phenotypic variants of disease. The researcher also will work on the seeded aggregation and replication of these amyloids isolated from human brain. Renewal of the appointment will be contingent on the availability of adequate funding and performance.

The University of California, Irvine is ranked among the nation’s best research institutes with over $90,000,000 in current funding. Enrichment opportunities abound through the Alzheimer’s Disease Research Center, the Memory Impairment and Neurodegenerative Disease Institute and the Center for the Neurobiology of Learning and Memory. Irvine has a pleasant climate, five miles from the beach.

Candidate performs research, provides university and/or public service, demonstrates professional competency and activity of high quality and significance.

Requirements:
• Ph.D. in biochemistry, cell biology or biophysics with experience in protein biochemistry is required.
• Experience working with amyloids and insoluble proteins and proteomic analysis are preferred.

Qualified candidates should submit their curriculum vitae, a cover letter, and the names and contact information of three references.

Qualifications

Basic qualifications (required at time of application)

Accepting all applicants.

Application Requirements

Document requirements
  • Curriculum Vitae - Your most recently updated C.V.

  • Cover Letter

  • Statement of Research (Optional)

  • Misc / Additional (Optional)

  • Sexual Misconduct, Harassment and Discrimination Declaration Form - All applicants of academic positions at the University of California, Irvine must download, complete, sign, and upload the following form with their application: Sexual Misconduct, Harassment and Discrimination Declaration Form
    (Optional)

Reference requirements
  • 3-5 required (contact information only)
Apply link: https://recruit.ap.uci.edu/JPF08238

About UC Irvine

The University of California, Irvine is an Equal Opportunity/Affirmative Action Employer advancing inclusive excellence. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC nondiscrimination policy.

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

Job location

Irvine, CA