Recruit

The UC Irvine Department of Otolaryngology seeks a part-time or full-time project scientist with experience in CRISPR to work on inner ear therapeutics in cell culture and animals. The successful candidate should have a background in molecular genetics and will be overseeing the design and implementation of inner ear therapeutics in cell culture and eventually animal models.

Responsibilities include but are not limited to:

• Hands-on experience analyzing DNA/RNAs methods or proteins (ELISA, qPCR, ddPCR, flow cytometry, western blot, and other techniques)
• Proficient in cell-based assays with various readout technologies, such as flow cytometry
• Proficient in molecular biology techniques common in upstream research, including molecular cloning, lentivirus production and titering, processing genomic DNA and RNA for downstream analysis
• Hands-on experience altering the genome of mammalian cells with gene editing and gene delivery techniques using CRISPR-based tools and beyond in viral vectors (AAV, lentiviral, adenovirus, etc) or mRNA
• Develop and execute assays for characterizing CRISPR delivery constructs such as cell type specificity & expression
• Experience in CRISPR work in animals preferred but not required
• Experience with hearing in animals is a plus but not required
• Collaborate across pre-clinical therapeutic groups and externally to drive the advancement of nucleic acid drug components
• Critically evaluate experiment data and communicate scientific findings as verbal presentations and written reports
• Aid in preparing presentations, reports, and journal/conference publications
• Assist with grant applications as needed

Submit your online application and complete curriculum vitae and 3 or more references by logging in to UC Irvine’s RECRUIT System, located at: https://recruit.ap.uci.edu

All applicants of academic positions at the University of California, Irvine must download, complete, sign, and upload the following form with their applications: Sexual Misconduct, Harassment and Discrimination Declaration Form

More information on the department can be found at http://www.ent.uci.edu/
For further information pertaining to this recruitment please contact:

Hamid Djalilian, Professor
333 City Bvld, Suite 525
Orange, California 92868-5386
Phone: 714-456-5591
Fax: 714-456-5747

The University of California, Irvine is an Equal Opportunity/Affirmative Action Employer advancing inclusive excellence. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC nondiscrimination policy.

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.